Mac Daddy's Cajun Venison Meatloaf

Ingredients
- 1 pound ground beef
- 1 pound ground venison
- 1 cup bread crumbs
- 1 egg
- 1/2 tsp crab boil
- 1/4 tsp liquid smoke
- 1/4 tsp salt
- 1/2 tsp Everglades seasoning
- 1/4 tsp cayenne pepper
- 1/4 tsp Cajun seasoning
- 1/4 tsp minced garlic
- 1 cup Cajun Trinity (onions, bell peppers, celery)
Step-by-Step Instructions
- Preheat oven to 350 degrees F. Grease a meatloaf pan.
- In a mixing bowl, combine all ingredients - the ground beef, ground venison, bread crumbs, egg, crab boil, liquid smoke, salt, Everglades seasoning, cayenne pepper, Cajun seasoning, minced garlic, and Cajun trinity. Mix until well blended.
- Put mixture in the greased meatloaf pan and compact meat firmly.
- Baste with Perfect Meatloaf Topping Sauce.
- Cook for about 50 minutes, or until internal temperature reaches 160°F.
- Serve with fresh homemade biscuits.
Common Problems and Solutions
Q: Why is my venison meatloaf dry?
A: Venison is very lean, which is why this recipe combines it with ground beef. Make sure not to overcook - pull it out when it hits 160°F internal temperature. You can also add an extra egg or a splash of milk to the mixture for added moisture.
Q: Can I make this without the Everglades seasoning?
A: Yes, Everglades seasoning (Monkey Dust) is a blend of salt, garlic, onion, and spices. If you don't have it, substitute with 1/2 tsp of garlic powder mixed with a pinch of onion powder and a bit more Cajun seasoning.
Tips and Techniques
Don’t overmix the meat mixture - this can make the meatloaf dense and tough. Mix just until ingredients are evenly distributed. Also, let the meatloaf rest for 5 minutes after baking before slicing to help it hold together better.
Ingredient Substitutions
- ground venison: ground elk, ground bison, or additional ground beef
- Everglades seasoning: garlic powder and onion powder
- Cajun Trinity: 1/3 cup each diced onion, bell pepper, and celery
Equipment Needed
- Mixing bowl
- Meatloaf pan
- Meat thermometer
Historical Context
In Cajun country, wild game like venison has always been a staple protein, and creative cooks have long worked it into traditional comfort food recipes. This meatloaf is a perfect example of adapting a classic American dish with Louisiana wild game and bold Cajun seasonings.






